PYRIDINE
PYRIDINE It is especially suitable for the dehalogenation, where it acts as the base of the elimination reaction and bonds the resulting hydrogen halide to form a pyridinium salt.
Pyridine Molecular Formula is C5H5N, its Hetrocyclic structure is similar to Benzene RING. Pyridine is an alkaline colorless, flammable liquid. Pyridine release unpleasant smell.
Properties: Pyridine is miscible with water It is a weak base It is highly flammable It has a distinctive, unpleasant fish-like smell
| PRODUCT NAME | : | PYRIDINE |
| CAS number | : | 110-86-1 |
| UN number | : | 1282 |
| Formula | : | NC4H4CH |
| Odour | : | PUNGENT |
| Solubility in water | : | COMPLETE |
| Density | : | 0.982 at 20 oC |
| Boiling point | : | 115 oC |
| Melting point | : | -42 oC |
| Viscosity | : | 0.97 cp at 20 oC |
| Flashpoint | : | 17oC |
| Explosive limits | : | 1.7 – 10.6 Vol% |
| Vapour pressure | : | 20 mbar at 20 oC |
| Skin absorption/irritation | : | 20 mbar at 20 oC |
| TLV Country NL Year 1995 | : | 5 ppm 15 mg/m3 |
| Pollution category 1994 | : | D |
Pyridine is used as a polar, basic, low-reactive solvent, for example in Knoevenagel condensations. It is especially suitable for the dehalogenation, where it acts as the base of the elimination reaction and bonds the resulting hydrogen halide to form a pyridinium salt.
Pyridine is a reasonable nucleophile for carbonyl groups and is often used as a catalyst in acylation reactions. ... The nitrogen atom in pyridine is nucleophilic because the lone pair of electrons on nitrogen cannot be delocalised around the ring.
