Antifoam 204
Mechanism of foam breakage by a defoamer. This inolves spreading of an water-insoluble surfactant on the bubble surfaces.
Antifoam function as an effective foam suppressor. Antifoam 204 contains 100% active components and is a mixture of organic non-silicone polypropylene-based polyether dispersions. It does not contain mineral oil. Antifoam 204 can itself be considered a surfactant, but it contains no other surfactants. This product is synthetic and not derived from animal or plant sources. Antifoam 204 can be sterilized repeatedly. The flow properties of Antifoam 204 are such that it can be pumped to a fermenter on an as-needed basis. For use in microbiological media, Sigma recommends a starting concentration of between 0.005% and 0.01%.
Antifoam 204 has been used:
- to suppress bubbling in thylakoid solutions during intramembrane isoprene quantification
- as a component of fed-batch continuous culture fermentation medium
- to suppress severe foaming in fermenter
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