TEMPO FREE RADICAL FOR SYNTHESIS
TEMPO FREE RADICAL FOR SYNTHESIS
As a stable aminoxyl radical, it has applications in chemistry and biochemistry. TEMPO is used as a radical marker, as a structural probe for biological systems in conjunction with electron spin resonance spectroscopy, as a reagent in organic synthesis, and as a mediator in controlled radical polymerization.
TEMPO is sufficiently inexpensive for use on a laboratory scale. There is also industrial-scale manufacturer which can provide TEMPO at a reasonable price in large quantity. Structurally related analogues do exist, which are largely based on 4-hydroxy-TEMPO (TEMPOL). This is produced from acetone and ammonia, via triacetone amine, making it much less expensive. Other alternatives include polymer-supported TEMPO catalysts, which are economic due to their recyclability.
