PYRIDINE AR
Pyridine is a reasonable nucleophile for carbonyl groups and is often used as a catalyst in acylation reactions. The nitrogen atom in pyridine is nucleophilic because the lone pair of electrons on nitrogen cannot be delocalised around the ring.
Pyridine is used to dissolve other substances. It is also used to make many different products such as medicines, vitamins, food flavorings, paints, dyes, rubber products, adhesives, insecticides, and herbicides. Pyridine can also be formed from the breakdown of many natural materials in the environment.
Over 100 medications on the market today include pyridine rings, such as Lunesta, commonly used to treat insomnia, Actos, commonly used to treat Type II diabetes, Nexium, commonly used to treat acid reflux, and Singulair, commonly used to treat asthma.
Pyridine is a reasonable nucleophile for carbonyl groups and is often used as a catalyst in acylation reactions. ... The nitrogen atom in pyridine is nucleophilic because the lone pair of electrons on nitrogen cannot be delocalised around the ring.
Pyridine is used as a polar, basic, low-reactive solvent, for example in Knoevenagel condensations. It is especially suitable for the dehalogenation, where it acts as the base of the elimination reaction and bonds the resulting hydrogen halide to form a pyridinium salt.
