ETHYL ACETO ACETATE FOR SYNTHESIS
ETHYL ACETO ACETATE FOR SYNTHESIS
Ethyl acetoacetate (CH3COCH2COOC2H5), also called acetoacetic ester, an ester widely used as an intermediate in the synthesis of many varieties of organic chemical compounds. Industrially it is employed in the manufacture of synthetic drugs and dyes. Ethyl acetoacetate is produced industrially by treatment of diketene with ethanol. The preparation of ethyl acetoacetate is a classic laboratory procedure. It is prepared via the Claisen condensation of ethyl acetate. Two moles of ethyl acetate condense to form one mole each of ethyl acetoacetate and ethanol.
Ethyl acetoacetate (Acetoacetic ester) is used in the synthesis of carboxylic acids, ketones, and heterocyclic compounds. (1) Synthesis of Alkylacetic Acids. This involves the reaction of sodium ethyl acetoacetate with an alkyl halide (RX) followed by acid hydrolysis.
